Ellison Medical Foundation Senior Scholars in Aging for 2010

The Ellison Medical Foundation is pleased to announce the Senior Scholar in Aging awardees for 2010. They are:

Shelley Berger, Ph.D.
University of Pennsylvania
High-throughput investigation of chromatin and epigenetic pathways regulating cellular lifespan

T. Keith Blackwell, M.D., Ph.D.
Joslin Diabetes Center
How TOR signaling influences SKN-1/Nrf stress defenses, stress resistance, and longevity

Gary Churchill, Ph.D.
The Jackson Laboratory
Aging Research Using the Diversity Outbred Mice

Fred H. Gage, Ph.D.
Salk Institute for Biological Studies
Mechanisms of Age-related decline in Adult neurogenesis

Todd E. Golde, M.D., Ph.D.
University of Florida
Proteinopathy-induced Neuronal Senescence and Inflammation

Richard Hanson, Ph.D.
Case Western Reserve University
The role of energy metabolism in the Prolonged Lifespan of the PEPCK-Cmus Mouse

Robert Haselkorn, Ph.D.
The University of Chicago
Determination of lifetimes of differentiated cells in filamentous cyanobacteria

David Holtzman, M.D.
Washington University in St. Louis
Sleep, aging, and Alzheimer’s disease (AD): Regulation of AD-associated proteins by sleep, aging, and orexin

Juan Carlos Izpisua Belmonte, Ph.D.
Salk Institute for Biological Studies
Using iPSC from HGPS patient fibroblasts to study ageing and dedifferentiation of senescence cells

Michael Karin, Ph.D.
University of California at San Diego
Role of Sestrins and autophagy in prevention of age-related myopathies

Konstantin Khrapko, Ph.D.
Beth Israel Deaconess Medical Center
Somatic mtDNA mutations in the aging process and longevity: an interspecies comparison

Junhyong Kim, Ph.D.
University of Pennsylvania
Genome Biology of Single Neuron Function and its Modulation with Age

Bruce Lahn, Ph.D.
The University of Chicago
Investigating the role of gene occlusion in cellular aging

Siu Sylvia Lee, Ph.D.
Cornell University
Probing the epigenetic determinants of longevity in C elegans

Haifan Lin, Ph.D.
Yale University
Piwi-piRNA Mechanism in Maintaining Genome Integrity and Longevity

Richard Miller, M.D., Ph.D.
University of Michigan
Two New Methods That Extend Maximal Lifespan in Mice

Tom Misteli, Ph.D.
National Cancer Institute
Molecular Mechanisms of Aging-related Cancer Formation

Scott Pletcher, Ph.D.
University of Michigan
Molecular dissection of neurosensory circuits that specify health and longevity in Drosophila

Liza Pon, Ph.D.
Columbia University
Mitochondrial-cytoskeletal interactions and aging

Peter Rabinovitch, M.D., Ph.D.
University of Washington
Protein translation, abundance, and turnover in genetic models of altered mTOR signaling

Michael Rosbash, Ph.D.
Brandeis University
Sleep and Aging in Drosophila: Cause and Effect

Nicholas Spitzer, Ph.D. (co-PI)
Davide Dulcis, Ph.D. (co-PI)
University of California at San Diego
Sensory Stimulation-Dependent Neurotransmitter Respecification in the Aging Brain

J. David Sweatt, Ph.D.
The University of Alabama at Birmingham
An epigenetic hypothesis of cognitive aging

Holly Van Remmen, Ph.D.
University of Texas Health Science Center at San Antonio
Mechanisms by which mitochondrial electron transport chain mutations lead to increased longevity in mice

Martin Walsh, Ph.D.
Mount Sinai School of Medicine
Long non-coding RNAs as epigenetic modulators of cellular aging

Thomas Wandless, Ph.D.
Stanford University
Protein Quality Control in Yeast and Mammalian Cells