The Ellison Medical Foundation Colloquium on the Biology of Aging

The Ellison Medical Foundation Colloquium on the Biology of Aging will be held Wednesday, August 8 through Friday, August 10, 2012 at the Marine Biological Laboratory, Woods Hole, MA. Ellison Medical Foundation Senior Scholars and New Scholars from 2008, now in the final year of their awards, will be presenting their research at the colloquium. These Colloquium presentations are open to the public. Directions to the MBL and travel information are available at http://www.mbl.edu/about/visit/directions/index.html.

The Ellison Medical Foundation
COLLOQUIUM ON THE BIOLOGY OF AGING
Wednesday, August 8 – Friday, August 10, 2012
Marine Biological Laboratory
Lillie Auditorium

 
AGENDA
 
 
Wednesday, August 8, 2012 
 
9:00 – 9:10               Introductions
 
9:10 – 9:45               Host-Microbe Interactions and Immunosenescence during Aging in C. elegans
                                    Dennis H. Kim, MIT (2008 New Scholar)
 
9:45 – 10:20              Unfolded Protein Response in Age-related Retinal Degeneration
                                    Hyung Don Ryoo, NYU (2008 New Scholar)
 
10:20 – 10:45           Break
                       
10:45 – 11:20           Control of proliferative plasticity in the adult intestine of Drosophila
                                    Heinrich Jasper, Univ. of Rochester (2008 Senior Scholar)
 
11:20 – 11:55           The role of autophagy and retromer genes in glp-1/Notch signaling
                                    Alicia Melendez, Queens College (2008 New Scholar)
 
11:55 – 12:30           The integrin-signaling complex – a novel longevity paradigm
                                    Malene Hansen, Sanford-Burnham Inst. (2008 New Scholar)
 
12:30 – 1:45              Lunch
 
1:45 – 2:20                Identifying the genetic basis of natural variation in stress and aging: genesis of a new nematode model system
                                    Patrick C. Phillips, Univ. of Oregon (2008 Senior Scholar)
 
2:20 – 2:55                Antagonistic Pleiotropy revealed in C. elegans JNK signaling
                                    Michael Shapira, UC Berkeley (2008 New Scholar)
 
2:55 – 3:30                Role of the amino acid sensor Gcn2 in the benefits of short-term dietary restriction against surgical stress in mice
Jay Mitchell, Harvard School of Public Health (2008 New Scholar)
 
  
Thursday, August 9, 2012
 
 
9:00 – 9:35                Dld Connects Mitochondrial Dysfunction With Longevity In The C. Elegans Mit Mutants
Shane L. Rea, Univ. of Texas San Antonio (2008 New Scholar)
 
9:35 – 10:10              Conserved longevity genes and mitochondrial stress 
Matt Kaeberlein, Univ. of Washington (2008 New Scholar)
 
10:10– 10:40            Break
 
10:40 – 11:15           Mitochondrial Modulation of Tissue Homeostasis and Longevity
David Walker, UCLA (2008 New Scholar)
 
11:15– 11:50            IRS2 increases mitochondrial dysfunction and oxidative stress in the CNS of the R6/2-mouse model of Huntington’s disease
Morris White, Children’s Hospital (2008 Senior Scholar)
 
11:50 – 12:25           Is the brain a control center of aging and longevity in mammals? - The function of hypothalamic SIRT1 and the NAD World
Shin-Ichiro Imai, Washington Univ. (2008 Senior Scholar)
 
12:30 – 1:45              Lunch
 
1:45 – 2:20                The significance and functional consequences of genetic loci associated with neurodegenerative disorders of the aging brain
Ornit Chiba-Falek, Duke Univ. (2008 New Scholar)
 
2:20 – 2:55                MicroRNAs responsible for memory decline and anxiety during brain aging
Tao Sun, Weill-Cornell Medical College (2008 New Scholar)
 
2:55 – 3:30                Translational studies of brain aging and neurodegenerative disease
Michela Gallagher, Johns Hopkins (2008 Senior Scholar)
 
 
Friday, August 10, 2012
 
 
9:00 – 9:35                RNA metabolism and genome stability
Karlene A. Cimprich, Stanford (2008 Senior Scholar)
 
9:35-10:10                Circadian regulation of LINE-1 retrotransposon
Victoria P. Belancio, Tulane (2008 New Scholar)
 
10:10 – 10:40           Break
 
10:40 – 11:15           Chromatin links to cellular senescence and malignant melanoma
Emily Bernstein, Mt. Sinai (2008 New Scholar)
 
11:15 – 11:50           DNA Damage and Stem Cell Quiescence
Steven C. Pruitt, Roswell Park Cancer Inst. (2008 Senior Scholar)
 
11:50– 12:25            How does the repair of biomolecules preserve physiological function in aging?
                                    Steven G. Clarke, UCLA (2008 Senior Scholar)
                                   
12:30 – 1:45              Lunch
  
1:45 – 2:20                Age-related accumulation of somatic structural changes in the nuclear genome of human blood cells in vivo
Jan Dumanski, Uppsala Univ. (2008 Senior Scholar)
 
2:20 – 2:55                Quantitative imaging of metabolism at any age in any system with multi-isotope imaging mass spectrometry (MIMS)
Claude Lechene, Brigham and Women’s (2008 Senior Scholar)
 
 
 
 
5th Annual Joshua Lederberg Lecture
8:00 pm Lillie Auditorium
Introduction by Gerald Weissmann, MD
 
Speaker
Leslie Vosshall, Ph.D.
The Rockefeller University
“Food and Sex: The Neurogenetics of Innate Behavior”
 

 

2013

2013