The Ellison Medical Foundation Colloquium on the Biology of Aging will be held Tuesday, August 9 through Thursday, August 11, 2011 at the Marine Biological Laboratory, Woods Hole, MA. Ellison Medical Foundation Senior Scholars and New Scholars from 2007, now in the final year of their awards, will be presenting their research at the colloquium. These Colloquium presentations are open to the public. Directions to the MBL and travel information are available at http://www.mbl.edu/about/visit/directions/index.html.

The Ellison Medical Foundation

COLLOQUIUM ON THE BIOLOGY OF AGING

Tuesday, August 9 – Thursday, August 11, 2011

Marine Biological Laboratory

Lillie Auditorium

AGENDA

Tuesday, August 9, 2011

9:00 – 9:10 Introductions

9:10 – 9:45 Utz Herbig, Ph.D.

UMDNJ

Telomere Dysfunction-Induced Senescence in Aging and Cancer

9:45 – 10:20 Emmanuel Skordalakes Ph.D.

Wistar Institute

Telomerase Structure Function

10:20 – 10:50 Break

10:50 – 11:25 Jan van Deursen, Ph.D.

Mayo Clinic College of Medicine

Inhibition of APC/CCdc20 by BubR1 regulates health- and life span

11:25 – 12:00 Avram Hershko, M.D., Ph.D.

Marine Biological Laboratory

Regulation of the APC/C ubiquitin ligase in the cell cycle: possible implications in aging

12:00 – 1:15 Lunch

1:15 – 1:50 Marion Schmidt, Ph.D.

Albert Einstein College of Medicine

Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae

1:50 – 2:25 Stephen Young, M.D.

University of California at Los Angeles

Fresh Insights into Nuclear Lamins and Laminopathies from Genetically Modified Mice

2:25 – 3:00 John Sedivy, Ph.D.

Brown University

The involvement of the c-Myc proto-oncogene in aging

Wednesday, August 10, 2011

9:00 – 9:35 Wei Gu, Ph.D.

Columbia University

p53 acetylation in tumor suppression and aging

9:35 – 10:10 Andrew Wurmser, Ph.D.

University of California at Berkeley

Glioma Cells Contribute to the Formation of Tumor Blood Capillaries

10:10– 10:40 Break

10:40 – 11:15 Rochelle Buffenstein, Ph.D.

University of Texas Health Science Center, San Antonio

Cancer Resistance And Genomic Stability In The Extraordinarily Long-Lived Naked Mole-Rat

11:15– 11:50 Alex Brodsky, Ph.D.

Brown University

Mechanisms from Genomics during Drosophila Aging

11:50 – 12:25 Anthony De Tomaso, Ph.D.

University of California at Santa Barbara

Aging and Regeneration in the Basal Chordate Botryllus schlosseri

12:30 – 1:45 Lunch

1:45 – 2:20 Sean Morrison, M.D.

University of Michigan

Maintenance of neurological function and adult stem cells by Bmi-1

2:20 – 2:55 Ronald Davis, Ph.D.

Scripps Research Institute

Age-dependent memory impairments analyzed by functional cellular imaging

2:55 – 3:30 Benjamin Eaton, Ph.D.

University of Texas Health Science Center, San Antonio

Increased presynaptic function by dietary restriction improves motor performance in a motor disease model

Thursday, August 11, 2011

9:00 – 9:35 Wulf Palinski, M.D.

University of California at San Diego

Targeting age-related diseases and aging mechanisms by interfering with maternal immunity and in utero programming

9:35-10:10 David Harrison, Ph.D.

The Jackson Laboratory

Testing the Hypothesis that Regulation of Female Reproductive Senescence is Cell Autonomous

10:10 – 10:40 Break

10:40 – 11:15 C. Ronald Kahn, M.D.

Joslin Diabetes Center, Harvard Medical School

Role of Adipose Tissue and miRNAs in Cell Non-Autonomous Regulation of Longevity and Stress Resistance Across an Evolutionary Spectrum

11:15 – 11:50 Adam Antebi, Ph.D.

Baylor College of Medicine

Nuclear hormone receptor control of the life plan and life span

11:50– 12:25 Heidi Tissenbaum, Ph.D. / A. J. Marian Walhout, Ph.D.

University of Massachusetts Medical School

Dissecting C. elegans insulins using a systems approach

12:30 – 1:45 Lunch

1:45 – 2:20 James Collins, Ph.D.

Boston University

A Network Biology Approach to Aging: Integrating Synthetic Biology and Systems Biology

2:20 – 2:55 Anthony Sauve, Ph.D.

Weill Medical College of Cornell University

Nicotinamide riboside is an endogenous neuroprotective agent that protects against mitochondrial dysfunction and genotoxic stress

2:55 – 3:30 David Sinclair, Ph.D.

Harvard Medical School

Insights into the importance of mitochondrial function in aging