| The Ellison Medical Foundation Colloquium on the Biology of Aging The Ellison Medical Foundation Colloquium on the Biology of Aging will be held Thursday, August 17 through Saturday, August 19, 2006 at the Marine Biological Laboratory, Woods Hole, MA. The Ellison Medical Foundation Senior Scholars and New Scholars from 2002, now in the final year of their awards, will be presenting their research at the colloquium. Those interested in attending can find directions at http://www.mbl.edu/inside/
AGENDA
Thursday, August 17, 2006
8:15 - 8:30
Introductions
8:30 - 9:05
Jacob Raber, Ph.D.
The Oregon Health & Science University
Gender and Isoform-Specific Effects of ApoE on Cognition in Humans
9:05 – 9:40
Michael Gordon Kaplitt, M.D., Ph.D.
Weill Medical College of Cornell University
Effect of PTEN Anti-Oncogene on Age-Related Neurodegenerative Disorders
9:40 – 10:15
Ya Ha, Ph.D.
Yale University School of Medicine
The Structural Basis of Intramembrane Proteolysis: Implications for Alzheimer’s Gamma-secretase
10:15 – 10:45 Break
10:45 – 11:20
Rudolph E. Tanzi, Ph.D.
Massachusetts General Hospital
Role of the Multiligand Receptor LRP in Alzheimer’s Disease-Related Neuropathogenesis: A Model for Age-Related Disorders Involving LRP
11:20 - 11:55
Tae-Wan Kim, Ph.D.
Columbia University
Genetic Studies of Factors Controlling Amyloid Production
11:55 - 1:00 Lunch
1:00 - 1:35
Giovanni Paternostro, M.D., Ph.D.
The Burnham Institute
Genetic Analysis of Cardiac Aging in Drosophila: A Systems Biology Approach
1:35 - 2:10
Thomas P. Sakmar, M.D.
The Rockefeller University
The Chromophore Regeneration Pathway in Age-Related Macular Degeneration
2:10 - 2:40 Break
2:40 - 3:15
Brad A. Rikke, Ph.D.
University of Colorado at Boulder
QTLs Specifying the Retardation of Reproductive Senescence by Dietary Restriction
3:15 - 3:50
Stephen Lyle, M.D., Ph.D.
University of Massachusetts Medical School
Molecular and Cell Biology of Adult Epithelial Stem Cells
Friday, August 18, 2006
8:00 - 8:35
Yidong Bai, Ph.D.
University of Texas Health Science Center at San Antonio
Molecular Remedy of Mitochondrial Deficiency
8:35 - 9:10
Stephen L. Helfand, M.D.
Brown University
Genetic Dissection of Aging in Drosophila
9:10 - 9:45
Cynthia J. Kenyon, Ph.D.
University of California, San Francisco
How Does Caloric Restriction Extend Lifespan?
9:45 - 10:20
James F. Nelson, Ph.D.
University of Texas Health Science Center at San Antonio
A New Murine Model for Longevity Assurance Is Associated with Ethanol Tolerance
10:20 - 10:50 Break
10:50 - 11:25
Gordon J. Lithgow, Ph.D.
The Buck Institute for Age Research
The Rapid Identification of Hormones and Pharmacological Compounds that Slow Aging in C. elegans
11:25 - 12:00
Antonio Bedalov, M.D., Ph.D.
Fred Hutchinson Cancer Research Center
Chemical Genetic Approaches to Aging
12:00 - 1:00 Lunch
1:00 - 1:35
Stuart Kim, Ph.D.
Stanford University Medical Center
Genomic approaches to studying aging in C. elegans
1:35 - 2:10
Thomas Kornberg, Ph.D
University of California, San Francisco
Toward a Comprehensive Assessment of Gene Expression during Development and Aging of Drosophila
2:10 - 2:45
David Walker, Ph.D. for Seymour Benzer, Ph.D.
California Institute of Technology
Mitochondrial Dysfunction in Drosophila
(David Walker & Seymour Benzer)
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Friday Evening Lecture
8:00p.m., Lillie Auditorium
Helen Blau, Ph.D.
Stanford University School of Medicine
Nuclear Reprogramming by Cell Fusion
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Saturday, August 19, 2006
8:00 - 8:35
Ari Gafni, Ph.D.
University of Michigan
Structure Induction in Heat Shock Factor 1, A Natively
Unfolded Transcription Factor
8:35 - 9:10
Ana Maria Cuervo, M.D., Ph.D.
Albert Einstein College of Medicine
Restoration of Chaperone-Mediated Autophagy Activity in Old
Rodents
9:10 - 9:45
Simon Melov, Ph.D
Buck Institute for Age Research
Critically Testing the Free Radical Theory of Aging, and Development of a Practical Intervention
9:45 - 10:15 Break
10:15 – 10:50
Stanley N. Cohen, M.D.
Stanford University School of Medicine
Genetic Mechanisms Regulating Replicative Aging in Differentiated Human Cell Populations
10:50 - 11:25
Woodring E. Wright, M.D., Ph.D
The University of Texas Southwestern Medical Center at Dallas
Functional Tests of Replicative Aging in Organotypic Skin Equivalents
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