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The Ellison Medical Foundation Colloquium on the Biology of Aging

The Ellison Medical Foundation
COLLOQUIUM ON THE BIOLOGY OF AGING
Monday, August 3 – Wednesday, August 5, 2009
Marine Biological Laboratory
Lillie Auditorium

AGENDA

Monday, August 3, 2009

8:15 – 8:30 Introductions

8:30 – 9:15
Ao-Lin Hsu, Ph.D .
University of Michigan
The Role of Heat-Shock Factor in the Regulation of Longevity

9:15 – 10:00
Pankaj Kapahi, Ph.D.
Buck Institute for Age Research
The Conserved role of the TOR Pathway in Mediating Lifespan extension by DR

10:00 – 10: 30 Break

10:30 – 11:15
Lawrence A. Donehower, Ph.D.
Baylor College of Medicine
Extension of Longevity in p53 Mutant Mice

11:15 – 12:00
Makoto Kuro-o, M.D., Ph.D.
University of Texas Southwestern Medical Center at Dallas
“The anti-aging mechanism mediated by klotho”

12:00 – 1:00 Lunch

1:00 – 1:45
S. Michal Jazwinski, Ph.D.
Tulane University Health Sciences Center
Aging in Natural Yeast Populations

1:45 – 2:30
Hartmut Geiger, Ph.D.
University of Cincinnati
Genomic Integrity and DNA-Repair Pathways in Aging Hematopoietic Stem Cells

2:30 – 3:15
D. Leanne Jones, Ph.D.
The Salk Institute for Biological Studies
Control of Germline Stem Cell Behavior During Aging

3:15 – 4:00
Norman Arnheim, Ph.D.
University of Southern California
Molecular Studies of the Paternal Age Effect

Tuesday, August 4, 2009

8:00 – 8:45
Irina M. Conboy, Ph.D.
University of California at Berkeley
Understanding the molecular mechanisms of stem cell aging

8:45 – 9:30
Erik Lee Snapp, Ph.D.
Albert Einstein College of Medicine
Age-related Oxidative Damage and the ER Folding Environment

9:30– 10:15
Alexei Tulin, Ph.D.
Fox Chase Cancer Center
Poly(ADP-ribosyl)ating enzymes in aging control

10:15 – 10:45 Break

10:45– 11:30
Josephine Hoh, Ph.D.
Yale University
Insights into Genetics of Age-Related Macular Degeneration

11:30 – 12:15
Siu Sylvia Lee, Ph.D.
Cornell University
Systematic Analysis of Genetic Determinants in C.elegans

12:15 – 1:15 Lunch

1:15 – 2:00
Norman Sharpless, M.D.
The University of North Carolina
Ink4a/Arf Expression in Aging

2:00 – 2:45
William G. Dunphy, Ph.D.
California Institute of Technology
Checkpoint Mediator Proteins as Potential Regulators of Senescence

 

2nd Annual Joshua Lederberg Lecture
8:00 pm Lillie Auditorium
Introduction by
Gerald Weissmann, M.D.
Speaker
David Baltimore, Ph.D.
California Institute of Technology
"MicroRNAs as Players in Immune and Inflammatory Responses"

 

Wednesday, August 5, 2009

8:00 – 8:45
Laura J. Niedernhofer, M.D., Ph.D.
University of Pittsburgh
The role of DNA repair in attenuating aging

8:45– 9:30
Judd M. Aiken, Ph.D.
University of Wisconsin-Madison
Mitochondrial DNA Abnormalities: Impact on Sarcopenia

9:30 – 10:15
Robert Alan Reenan, Ph.D.
Brown University
Genetic Recoding by RNA Editing and the Aging Process

10:15 – 10:45 Break

10:45 – 11:30
S. Kerry Kornfeld, M.D., Ph.D.
Washington University School of Medicine
The anticonvulsant ethosuximide disrupts sensory function to extend C.elegans lifespan

11:30 – 12:15
Charles V. Mobbs, Ph.D.
Mount Sinai School of Medicine
CBP and SATB-1 expression predict, and mediate effects of dietary restriction on, lifespan

12:15 – 1:15 Lunch

1:15 – 2:00
John E. Repine, M.D.
University of Colorado Health Science Center
Oxygen Tolerance, the Metabolic Syndrome, Longevity and Mitochondrial Function

2:00 – 2:45
Bruce A. Yankner, M.D., Ph.D.
Harvard Medical School
Evolution of the Aging Brain Transcriptome

2:45 – 3:30
Stephen F. Heinemann, Ph.D.
Salk Institute for Biological Studies
Alzheimer's disease: New Approaches to Therapy