One of the major functions of cellular senescence is to serve as a brake against malignancy. At least 3-6 mutations are required to form a tumor. Each mutation probably requires 20-30 doublings for the initial mutation, elimination of the remaining wild-type allele (for recessive tumor suppressor genes) and expansion to a population...
Senior and New Scholars Awards for University of Texas Southwestern Medical Center
Dr. Woodring E. Wright
University of Texas Southwestern Medical Center
2002 senior Scholar Award in aging
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Dr. Vanessa Sperandio
University of Texas Southwestern Medical Center
2004 new Scholar Award in gid
Enterohemorrhagic E. coli (EHEC) is a global public health problem, causing bloody diarrhea and hemolytic uremic syndrome (HUS) throughout the world. EHEC activates expression of its virulence genes via cell-to-cell signaling in response to signals produced by the normal intestinal flora and host-hormones. The goal of this proposal is to...
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Funded Institutions
The Ellison Medical Foundation fosters research by means of grants-in-aid on behalf of investigators to universities and laboratories within the United States. Institutions receiving awards must be tax-exempt 501(c)(3) organizations or U.S. colleges or universities.
The Ellison Medical Foundation