The unique ability of stem cells to produce large numbers of many different cell types in the body make them an extremely valuable tool in regenerative medicine. However, since cells accumulate genetic defects with age, stem cells derived from older individuals may be more limited in their utility. Stem cell therapy could therefore fail to help...

Loss of reproductive fitness is a hallmark of aging, conserved from yeast to humans. Not only does aging result in fewer progeny, it can also affect ìquality,î as progeny produced late in life may be inviable or otherwise less fit. Women over a certain age are at a higher risk for miscarriages or children with developmental disorders, such as...