Mechanisms that suppress the activities associated with cellular growth and proliferation, such as senescence and apoptosis, which fundamentally rely on the activities of tumor suppressor loci such as TP53 and INK4α/ARF also contribute to the deterioration in the reproductive function of many cell types with advancing age....
Senior and New Scholars Awards for Mount Sinai School of Medicine
Dr. Martin Walsh
Mount Sinai School of Medicine
2010 senior Scholar Award in aging
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Dr. Emily Bernstein
Mount Sinai School of Medicine
2008 new Scholar Award in aging
Chromatin, the complex of DNA and associated proteins, is the physiological form of our genome. Chromatin is a dynamic template governed by intricate regulation, the mechanisms of which are just beginning to unfold. The basic fundamental repeating unit of chromatin is the nucleosome, which consists of approximately 146 base pairs of DNA wrapped...
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Dr. Qiang Zhou
Mount Sinai School of Medicine
2006 new Scholar Award in aging
One of the hallmarks of the aging process is the decline of learning and memory functions evidenced by slower learning and faster forgetting. Since alterations in synaptic modifications (long-term potentiation or long-term depression) have been observed in the aged animals, deficits may exist in the transition from short-term to long-lasting...
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Dr. Peter Palese
Mount Sinai School of Medicine
2003 senior Scholar Award in gid
Viruses can only replicate in live cells, and they rely on the host cell machinery for the amplification of their viral components. Because viral infection is usually detrimental to the host cell, the cell has evolved defense mechanisms which prevent replication of invading viruses. An intricate relationship exists between cellular defenses and... |
Dr. Christopher F. Basler
Mount Sinai School of Medicine
2002 new Scholar Award in gid
Viruses have evolved ways to counteract the host innate immune response. Of particular importance are viral products which inhibit the antiviral activity of the type I interferon system. Such “interferon-antagonists” are essential for the virulence of several “model” viruses including influenza virus, Sendai virus, vaccinia virus and herpes...
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Funded Institutions
The Ellison Medical Foundation fosters research by means of grants-in-aid on behalf of investigators to universities and laboratories within the United States. Institutions receiving awards must be tax-exempt 501(c)(3) organizations or U.S. colleges or universities.
The Ellison Medical Foundation