Aging of the Musculoskeletal System
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2010 senior Scholar Award in aging
Loss of muscle mass and degeneration of the fibers that make up skeletal muscle, a condition called sarcopenia, are major hallmarks of aging. Muscle loss and degeneration contribute to many other ill-effects of aging including frequent bone fractures and insulin resistance, a pre-diabetic condition... >> MORE |
2009 new Scholar Award in aging
Sarcopenia, or degenerative loss of skeletal muscle mass and function, is an increasing health concern in the United States, causing elderly people to sacrifice their independence and rely on institutionalized care due to immobility and loss of strength. Although reductions in both the size and... >> MORE |
2009 new Scholar Award in aging
Organismal aging is characterized by a decline in regenerative capacity leading to reduced physiological function. Skeletal muscle has an impaired regenerative response during aging, largely due to defects in the muscle stem cells (the satellite cells), which are almost solely responsible for... >> MORE |
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2008 new Scholar Award in aging
Over 20 million people in the United States suffer from osteoarthritis, a degenerative joint disease in articular cartilage with increased incidence observed with age. This disease often reduces an individualís ability to function as a result of inflammation, pain, and decreased mobility.... >> MORE |
2001 new Scholar Award in aging
Sarcopenia, progressive loss of muscle mass and quality, is the principle component of the profound
changes in body composition that occur with aging, and it is a large factor in loss of strength, deficits in
gait, and reduced metabolic rate in the elderly. We will apply two novel methods to... >> MORE |
The Ellison Medical Foundation