1998 New Scholar Award in Aging

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1998 New Scholar Award in Aging
Dr. Cole's research is devoted to evaluating the effects of melatonin on mammalian physiology. Melatonin is a hormone thought to be important in the regulation of circadian rhythm. It is taken as a medication by some travelers to prevent jet lag. Melatonin has even been speculated to be useful...  >> MORE
1998 New Scholar Award in Aging
Dr. Golde compares Alzheimer's disease (AD) to atherosclerosis. Both are diseases associated with aging, both have strong genetic components, and both are diseases of deposition. Atherosclerosis involves deposition of cholesterol within blood vessels, which damages the cardiovascular system....  >> MORE
1998 New Scholar Award in Aging

In the US, 5% of women over age 60, and 28% over 85 may have dementia. While advances have been made recently to delay Alzheimer's disease progression, little population-based research is aimed at studying the earliest stages of cognitive decline in healthy elderly, a stage which might be most...  >> MORE

1998 New Scholar Award in Aging

Apoptosis is a genetically regulated form of cell death which is critical for the normal development and adult function of multicellular organisms. Inappropriate activation of apoptosis also contributes to the neuronal cell loss associated with acute brain injuries such as stroke, and in age-...  >> MORE

1998 New Scholar Award in Aging
The capacity of the central nervous system (CNS) to modify connectivity properties as a result of activity is termed plasticity. Plasticity is not only a prominent feature of CNS development, but in the adult brain underlies learning and memory processes and adaptive reorganization of primary...  >> MORE
1998 New Scholar Award in Aging

Werner syndrome (WS) is a rare genetic disorder associated with premature aging and increased risks for cancer. The gene underlining WS has been cloned and found to encode a member of the RecQ DNA helicase family. In addition to the drastic mutations found in WS patients, there are also...  >> MORE